Which statement is NOT true about ACE inhibitors?

The correct answer highlights that ACE inhibitors do indeed prevent vasoconstriction and hormone activation, making the statement about them not being true incorrect. ACE inhibitors, or angiotensin-converting enzyme inhibitors, function by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This action leads to vasodilation, which helps lower blood pressure and reduces the workload on the heart.

Additionally, the mechanism of action of ACE inhibitors does involve the reduction of hormone activation related to the renin-angiotensin-aldosterone system, which plays a critical role in regulating blood pressure and fluid balance in the body. Therefore, the statement that suggests they prevent these physiological responses is, in fact, true.

In contrast, the other statements about ACE inhibitors are accurate. These medications typically have names that end in "pril," which is a well-known naming convention. Orthostatic hypotension is a recognized side effect due to their blood pressure-lowering effects, particularly upon standing. Lastly, they do help in reducing fluid overload, which can be beneficial for patients with heart failure or hypertension, as they increase urinary output by decreasing the reabsorption of sodium and water.

Because of these factors, the