Which statement is not true about calcium channel blockers?

The statement regarding how calcium channel blockers (CCBs) usually decrease exercise performance in patients with hypertension is not true. In fact, CCBs are often used to improve exercise tolerance in patients with hypertension by reducing peripheral vascular resistance and promoting vasodilation. This can lead to better blood flow and oxygen delivery during physical activities, which can enhance exercise performance rather than diminish it.

The side effects commonly associated with calcium channel blockers, such as swelling in the feet and ankles, and fatigue, align with the known pharmacological effects of these medications. Additionally, monitoring heart rate, especially when medications are adjusted or changed, is crucial to ensure that it remains stable and does not exceed a safe increase. CCBs are significant for their property of promoting vasodilation and, under certain circumstances, can stabilize heart rate. Thus, while the other statements reflect accurate information regarding the effects and management of CCBs, the notion that they typically decrease exercise performance contradicts their intended clinical benefits in managing hypertension and enhancing activity levels in patients.