Which pulse pressure level indicates higher mortality?

A pulse pressure above 60 mmHg is associated with higher mortality, particularly in older adults and those with cardiovascular disease. Pulse pressure is calculated as the difference between systolic and diastolic blood pressure. An elevated pulse pressure may indicate increased stiffness of the aorta and other large arteries, which is often seen with aging and various medical conditions. High pulse pressure can reflect inadequate blood flow to the organs and may signal underlying cardiovascular issues, leading to a greater risk of adverse health outcomes, including mortality.

This increased mortality risk is particularly relevant in geriatric populations, where aging-related changes in vascular compliance exacerbate the impact of elevated pulse pressure. Older adults tend to have stiffer arteries, which can produce higher systolic pressure while diastolic pressure may not rise as significantly, leading to a wider pulse pressure. Addressing this aspect of blood pressure can be crucial for risk stratification and management in geriatric patients.