Which of the following best describes the impact of aging on fibroblasts?

The aging process significantly affects fibroblasts, which are crucial in maintaining the extracellular matrix and tissue repair. As individuals age, the number of fibroblasts tends to decrease. This decline contributes to several age-related changes in connective tissue, including reduced collagen production, which can lead to decreased skin elasticity, slower wound healing, and diminished tissue regeneration capabilities.

Additionally, the decrease in fibroblasts can adversely impact the structure and function of various tissues, which is a critical concern in geriatric health. By understanding this decrease, healthcare providers can better address issues related to aging, such as skin aging and the healing processes in older adults.