What is a primary cause of sarcopenia?

Sarcopenia refers to the age-related loss of muscle mass and strength. Physical inactivity is a primary cause of sarcopenia because regular muscle use and physical activity are critical for maintaining muscle mass and overall strength. As individuals age, many may reduce their levels of physical activity due to various factors, including health conditions, decreased motivation, or fear of injury. This sedentary lifestyle leads to muscle disuse, ultimately contributing to muscle atrophy and the progression of sarcopenia.

While factors such as loss of alpha-motor neuron input, declines in hormonal levels, and protein deficiency do play roles in muscle health, their contributions are often secondary to the overarching impact of inactivity. Specifically, without regular engagement in activities that stimulate muscle fibers, the benefits of hormonal and nutritional support are less effective in preventing muscle loss. Thus, encouraging physical activity is essential in combating sarcopenia and promoting healthy aging.