What complication may arise from steroid use in transplant patients?

Steroid-induced myopathy is a well-documented complication that can arise from the use of corticosteroids in transplant patients. These medications are frequently prescribed to help prevent rejection of the transplanted organ by suppressing the immune system. However, one significant side effect of long-term steroid use is the weakening of skeletal muscles, which is often referred to as steroid-induced myopathy.

This condition manifests as muscle weakness, particularly in the proximal muscles, which can significantly impair mobility and functional ability in individuals, especially in the elderly population who may already have compromised muscle strength and mass. This weakening occurs due to various mechanisms, including muscle fiber atrophy and alterations in protein synthesis, which are exacerbated by the catabolic effects of the steroids.

Other options are not applicable complications related to steroid use in this context. For example, while steroids may have effects on healing and muscle strength in certain contexts, they typically do not lead to accelerated healing or enhanced muscle strength in transplant patients; rather, the opposite is often true. Additionally, corticosteroids are generally associated with decreased cardiovascular endurance rather than improvements. Thus, understanding the risks of steroid-induced myopathy is crucial for managing and rehabilitating transplant patients effectively.